gantt
dateFormat YYYY-MM
section Mandatory courses
Medical Research Ethics :active 2025-01, 2025-02
Basic Laboratory Safety :active 2025-01, 2025-02
Introduction to Doctoral Education at KI :active 2025-01, 2025-02
Basic Course in Medical Statistics :active 2025-02, 2025-03
Present your Research! :active 2025-08, 2025-09
Quality Assurance of Clinical Research :active 2025-09, 2025-10
section Project specific courses
Statistical Methods with R :active 2024-09, 2024-12
Programing in Python :active 2024-08, 2024-11
Endothelial Cell Function[...] :active 2026-02, 2026-03
Intermediate Medical Statistics :active 2026-03, 2026-04
Cellular Signalling :active 2026-04, 2026-05
section Clinical studies
Microangiopathy IN Diabetes(MIND) :active 2024-01, 2026-01
Capillary dysfunction in Sepsis(CapriS) :active 2024-01, 2027-01
SCAPIS2Spectrum - Microcirculation substudy :active 2024-06, 2029-01
section Journal clubs
IMA-journal clubs :active 2024-06, 2029-01
section Conferences
European Society on Microcirculation :active, milestone 2025-05, 2025-06
ISICEM :active, milestone 2026-03, 2026-04
European Society on Microcirculation :active, milestone 2027-04, 2027-05
section Significant Milestones
Start date :milestone, 2024-08, 2024-08
Half Time Control :milestone, 2026-08, 2026-08
Dissertation Defence :milestone, crit, 2029-05, 2029-05
Individual study plan
Bedside assessment of microvascular dysfunction
method evaluation in clinical studies 
Disposition
Introduction and Background: Introduction to the topic, research objectives
Research plan and Methodology: Study designs, methods and analysis
Timeline and Milestones: Project timeline with key milestones
Resources and Support: Overview of resoruces and support
Discussion and Feedback: Opporunity for audience feedback
Introduction and Background
Relevance
Introduction and Background
Relevance
Key Areas: Cardiovascular disease, diabetes, heart failure, sepsis
Clinical Implications
Early Detection and Prevention: Monitoring microvascular function helps identify patients at high risk, enabling early intervention and preventive measures.
Disease Progression and Treatment Monitoring: Microvascular assessment provides a window into disease activity, aiding in the evaluation of treatment effectiveness.
Goal-directed therapy: Insights into microvascular health support goal-directed therapies, optimizing treatment plans tailored to individual needs.
Introduction and Background
Problem
Current methods
Capillary refill time Subjectivity, variability, sens/spec, non-quantifiable*
Coronary angiography Invasive, cumbersome, resource intensive, organ specific
Stress Cardiac MRT Cumbersome, resource intensive, organ specific
Biomarkers Analysis time, interpretation, resource intensive
Introduction and Background
Problem
Future methods - what is needed?
Quantitative Precision and comparison
Non-invasive Risk and discomfort
Low variability and High sensitivity Consistency and precision
Rapid and ease of use Clinical convenience
Organ-agnostic Systemic dysfunction
Cost-effective Iterative usage and goal-directed
Research plan and Methodology
.
Timeline and Milestones
Resources and Support
- Summary: Key points discussed.
Challanges and Risk Management
- Many challanges wow
Discussion and Feedback
- So much feedback!